None listed
Conditions
Interventions
Intervention1: human milk fortification early versus late: Slow advancement with late fortification: infants in this group will be started feeds at @ 20ml/kg/day and advanced at the same rate to 140ml
Sponsors
Dr Anitha Haribalakrishna
Eligibility
Inclusion criteria
Inclusion criteria: any preterm infant > 30 weeks gestation with birth weight between 1 to 1.5 Kg will be eligible
Exclusion criteria
Exclusion criteria: 1.preterm with congenital anomalies 2. those with respiratory distress at the time of enrollment 3. those on inotropic support during feed initiation 4. severe birth asphyxia 5. requirement of mechanical ventilation 6. surgical neonates 7. absent or reverse end diastolic flow in antenatal Doppler
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to regain birth weight.Timepoint: baseline, 2 weeks and 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ time to reach full enteral feeds: a feed volume of 140ml/kg/day â?¢ duration of intravenous fluids â?¢ duration of hospital stay â?¢ incidence of NEC: as per Bellâ??s stage â?¥2 â?¢ incidence of feed intolerance: increase in abdominal girth by 2cm, altered aspirates 50% feed volume â?¢ incidence of sepsis: Late onset sepsis if any two sepsis screen parameters are positive â?¢ mortality. Timepoint: baseline, 2 weeks and 4 weeks | — |
Countries
India
Contacts
Public ContactDr Anitha Haribalakrishna
Seth GS Medical College and KEM Hospital
Outcome results
None listed