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Effects of nerve mobilisation and exercise on Diabetic Peripheral Neuropathy patients

"Study on the effects of Neural Mobilisation and exercises on Neuromuscular properties in subjects with Diabetic Peripheral Neuropathyâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043564
Enrollment
84
Registered
2022-06-29
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E104- Type 1 diabetes mellitus with neurological complications Health Condition 2: E114- Type 2 diabetes mellitus with neurological complications

Interventions

Intervention1: Neural mobilization: Neural mobilisation of the tibial and peroneal nerve of the lower limb in supine and side lying position will be given. The interventions will be given 3 sessions/w

Sponsors

Centre for Physiotherapy and Rehabilitation Sciences Jamia Millia Islamia Central university
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects diagnosed with diabetes mellitus detected at least 5 years or before the enrolment. 2. MDNS score >= 6 will be included. 3. MMSE > 24 4. Ability to walk independently household distances without assistive device.

Exclusion criteria

Exclusion criteria: 1.History of neurological symptoms other than that of diabetic peripheral neuropathy (i.e., hemiparesis, myelopathy, cerebellar ataxia, etc.) 2.History of cardiovascular disease (angina, breathlessness, uncontrolled hypertension). 3.Significant musculoskeletal deformity (amputation, scoliosis, severe osteoarthritis). 4.Lower extremity arthritis that limits standing or weight bearing position. 5.Symptomatic postural hypotension (standing up to 5 min). 6.Evidence of vestibular dysfunction. 7.Unstable proliferative retinopathy. 8.Vascular complications (venous or arterial ulcers) 9.Receiving any physical therapy intervention.

Design outcomes

Primary

MeasureTime frame
Blood glucose level, Glycosylated haemoglobin (HbA1c),motor and sensory Nerve conduction velocity (tibial and sural nerve),Fatigue of lower limb muscles,TNF-α, NPRSTimepoint: At baseline (pre-intervention) and at 8 weeks (post-intervention)—

Secondary

MeasureTime frame
NPRS, Quality of life,Timepoint: At baseline(pre-intervention) and at 8 weeks (post-intervention)—

Countries

India

Contacts

Public ContactDr Majumi M Noohu PhD

Jamia Millia Islamia (Central university), New Delhi, India.

mnoohu@jmi.ac.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026