Health Condition 1: K352- Acute appendicitis with generalized peritonitis Health Condition 2: K251- Acute gastric ulcer with perforation Health Condition 3: K650- Generalized (acute) peritonitis Health Condition 4: K566- Other and unspecified intestinal obstruction Health Condition 5: K631- Perforation of intestine (nontraumatic)
Conditions
Interventions
Intervention1: 80 percent FiO2 perioperatively: Patients in the intervention arm will receive inspired oxygen at a concentration of 80 percent after endotracheal intubation (FiO2 of 0.80). After emerg
Sponsors
AIIMS Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-65 years 2. ASA I or II 3. Undergoing emergency laparotomy for perforation peritonitis or obstruction
Exclusion criteria
Exclusion criteria: 1. Patients 65 years 2. Patients who cannot maintain saturation >90% in room air in the preoperative period 3. Patients who are intubated before induction due to respiratory failure 4. Patients who cannot be extubated in the post operative period 5. Patients with a known history of chronic respiratory/cardiac disease 6. Patients with moderate or severe COVID Disease 7. Patients who are currently pregnant 8. Patients unwilling to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Incidence of deep and organ space SSI within 30 postoperative days [Day 0 being the day of the procedure]Timepoint: 30 postoperative days | — |
Secondary
| Measure | Time frame |
|---|---|
| Admission to ICUTimepoint: 14 postoperative days;ASEPSIS ScoreTimepoint: 30 postoperative days;Incidence of pulmonary complications causing symptoms of atelectasis, pneumonia, respiratory failureTimepoint: 14 postoperative days;Post operative duration of hospital stayTimepoint: 30 postoperative days;Re-operationTimepoint: 14 postoperative days | — |
Countries
India
Contacts
Public ContactDr Pravanjan Behera
All India Institute of Medical Sciences, Bhubaneswar
Outcome results
None listed