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To compare the occurrence of fall in blood pressure after spinal anaesthesia among normal pregnant women and pre-eclamptic women who are undergoing cesarean section

Comparison of incidence of spinal anaesthesia induced hypotension between patients with severe preeclampsia and low risk pregnant women undergoing emergency caesarean delivery: a prospective cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/06/043517
Enrollment
142
Registered
2022-06-27
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

None listed

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: (Group 1) Women with severe preeclampsia undergoing emergency caesarean section under spinal anaesthesia. (Group 2) Low risk pregnant women undergoing emergency caesarean section under spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1.NICE 1 planned for General anaesthesia 2.Patients who received labour analgesia planned for LSCS

Design outcomes

Primary

MeasureTime frame
Incidence of post spinal hypotension in both the groups. ( 20 % reduction in the baseline MAP) w678Timepoint: Every minute until 20 minutes after spinal anaesthesia administration—

Secondary

MeasureTime frame
1) Comparison of total dose of vasopressors used in managing post spinal hypotension between two groups. 2) Comparison of serum magnesium, serum uric acid, serum endothelin 1(ET I) and urine norepinephrine (NE) to incidence of hypotension in severe pre-eclampsia. 3) Comparison of neonatal outcomes (Apgar score, cord blood pH estimation, base deficit and serum bicarbonates) between the groups Timepoint: 1) Intaoperatively when hypotension is noted 2) Pre-operative blood sample 3) End -opertive/immediately after child birth—

Countries

India

Contacts

Public ContactVarun Nair

JIPMER

varunloyolite@gmail.com6282124558

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026