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Local lignocaine application to decrease cough reflex in laryngeal surgeries

Topical laryngeal application of lignocaine to decrease cough reflex during extubation in microlaryngeal surgeries:A randomised controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043493
Enrollment
50
Registered
2022-06-27
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Lignocaine 4%: Topical application over the vocal cords for 5 minutes, before extubation Control Intervention1: Saline: Topical application on the vocal cords for 5 minutes, before extu

Sponsors

AIIMS Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists Physical status I & II 2. BMI 3. Scheduled for microlaryngeal surgeries, under balanced general anesthesia. 4. Patients in which standard induction technique using intravenous agents and muscle relaxants followed by tracheal intubation is planned.

Exclusion criteria

Exclusion criteria: 1. Local anesthetic allergy. 2. Upper airway inflammatory symptoms during the previous week. 3. Symptomatic gastric reflux despite medication. 4. Pulmonary disease. 5. Patients in which a different plan of extubation is planned in view of difficult airway.

Design outcomes

Primary

MeasureTime frame
Cough reflexTimepoint: 5 minutes after extubation—

Secondary

MeasureTime frame
heart rate , blood pressureTimepoint: at 0, 2 and 5 minutes after extubation. ;sore throatTimepoint: 1 hour of extubation—

Countries

India

Contacts

Public ContactAbhyuday Kumar

AIIMS Patna

drabhyu@gmail.com9013512403

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026