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Influence of interdialytic weight gain, oxidative stress, and inflammation on hospitalization rate and mortality in maintenance hemodialysis individuals

Impact of interdialytic weight gain, oxidative stress and inflammation on hospitalization rate and mortality in maintainance hemodialysis individuals - A Cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/06/043472
Enrollment
107
Registered
2022-06-24
Start date
Unknown
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N00-N99- Diseases of the genitourinary system

Interventions

None listed

Sponsors

Kasturba Medical college Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All stable individuals who are undergoing maintenance hemodialysis

Exclusion criteria

Exclusion criteria: Post-transplant patients with graft failure Patients on other dialysis modalities Patients with malignancy Patients with liver disease Patients with chronic inflammatory disorders (Tuberculosis, rheumatoid arthritis vasculitis) Patients with active infections/ hospitalization 3 months before enrolment HIV, HCV, and HbsAg positive patients Patients taking or have received anti-oxidants, steroids, and immunosuppressive medications in the last 6 months Pregnancy

Design outcomes

Primary

MeasureTime frame
1. Quantity of interdialytic fluid gain, oxidative stress, and inflammation in maintenance hemodialysis individuals and evidence for their impact on hospitalization rate and mortality 2. Relationship between interdialytic fluid gain, oxidative stress, and inflammation Timepoint: One year six months

Secondary

MeasureTime frame
1. Relationship of interdialytic fluid gain, oxidative stress, and inflammation with Renal anemia 2. Relationship between oxidative stress and mineral bone disease Timepoint: One year six months

Countries

India

Contacts

Public ContactDr Ravindra Prabhu A

Kasturba medical college MAHE Manipal

ravindra.prabhu@manipal.edu9448107771

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026