Health Condition 1: I501- Left ventricular failure, unspecified
Conditions
Interventions
Intervention1: Drug trial: The deficiency of iron is calculated using Ganzoni formula. The required dose is given intravenously in the form of ferric carboxymaltose, each time not more than 1000mg. If
Sponsors
PGIMER CHANDIGARH
Eligibility
Inclusion criteria
Inclusion criteria: Age � 18 years. Patients with LVEF Iron deficiency, defined as either serum ferritin Patients who give consent.
Exclusion criteria
Exclusion criteria: Any clinically overt bleeding (gastrointestinal bleeding, hypermenorrhoea, history of peptic ulcer without evidence of healing or inflammatory intestinal diseases). Any inflammatory, neoplastic or infectious disease. Recent myocardial revascularization procedures. Active or metastatic neoplastic disease. Age ââ?°Â¤18 years. Patients/patientââ?¬•s attender who refuse to give consent. Unknown patients. Any contraindications to IV iron therapy Anemia not attributable to iron deficiency. Iron overload. Prior hypersensitivity reactions to intravenous iron therapy. Acute or chronic infection. Pregnancy- 1st trimester. Acute Kidney Injury. Patients with a history of severe asthma, eczema or other atopic allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in 6-min-walk-test (6MWT) distance from baseline to Week four after IV iron therapy.Timepoint: Change in 6-min-walk-test (6MWT) distance from baseline to Week four after IV iron therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| 🠶 Improvement in New York Heart Association class at 4 weeks. 🠶 Rate of HF-related or other cardiovascular hospitalizations at 12 weeks. 🠶 Time to death for any reason by 12 weeks. Timepoint: 12 weeks | — |
Countries
India
Contacts
Public ContactSharath Chandra
PGIMER, Chandigarh
Outcome results
None listed