A pilot study to evaluate the efficacy of Phalatrikadi Ghana Vati in patients of Non - alcoholic fatty liver disease

Evaluation of efficacy of Phalatrikadi Ghana Vati in Patients of Non -alcoholic fatty liver disease through reverse pharmacology approach

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/06/043428

Enrollment

Registered

2022-06-22

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Ultrasonography (USG) abdomen suggestive of NAFLD with or without symptoms like pain in right upper quadrant/epigastric region of the abdomen, feeling of nausea, and vomiting, loss of appetite, burning sensation in the abdomen. 2.Liver function tests showing raised alanine transaminases (ALT) or aspartate transaminases (AST) levels raised above the normal limits (40IU/L) up to 300 IU/L

Exclusion criteria

Exclusion criteria: 1. Patients unwilling to participate in study 2. Patients with a history of alcohol intake exceeding 20 g/day (Alcohol consumption history shall be separately obtained from the patients and family) 3. Patients testing positive for markers of other viral hepatitis

Design outcomes

Primary

Measure	Time frame
Improvement in symptoms Udarasula (pain in abdomen), utklesa (feeling of nausea and vomiting), agnimandya (impaired digestion), klama (Fatigue), aruci (loss of appetite), sadana (malaise) & Improvement in USG for NAFLD Improvement in BMI, ALT, AST & ALT/AST Ratio & Lipid ProfileTimepoint: baseline And 84 days	—

Secondary

Measure	Time frame
1. mprovement in symptoms Udarasula (pain in abdomen), utklesa (feeling of nausea and vomiting), agnimandya (impaired digestion), klama (Fatigue), aruci (loss of appetite), sadana (malaise)Timepoint: Baseline, 28th day, 56th day and 84 days	—

Countries

India

Contacts

Public ContactProf Anil Sharma

MAHATMA GANDHI AYURVED COLLEGE HOSPITAL RESEARCH CENTRE SALOD HIRAPUR WARDHA MAHARASHTRA

bharatrathi174@gmail.com9011058301

Outcome results