Health Condition 1: C15-C26- Malignant neoplasms of digestive organs
Conditions
Interventions
Intervention1: Contrast Enhanced Ultrasound (CEUS) Guided Celiac plexus nerve block: Under CEUS guidance, celiac plexus nerve is blocked using neurolytic agent through anterior abdominal approach for
Sponsors
AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Males or females with upper abdominal malignant tumours diagnosed by histopathology or imaging. 2. A score of more than 7 on a 10 point Visual Analog Scale (VAS) for abdominal pain. 3. Unresectable tumours.
Exclusion criteria
Exclusion criteria: 1. Poor condition (unstable vitals) 2. Widely metastasizing tumour in peritoneum involving the celiac plexus and infiltrating abdominal wall/ peritoneum causing somatic pain. 3. Non-correctable coagulopathy and thrombocytopenia. 4. Massive ascites 5. Known allergic reaction to specific agents. 6. Uncontrolled hypertension 7. Recent MI or unstable angina.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Contrast enhanced ultrasound guided celiac plexus neurolysis alleviates pain due to upper abdominal cancer pain in 80% of patients who underwent the procedure.Timepoint: Pain status is assessed - immediately , on day 1 , 1 week , 1 month and 3 months after procedure using VAS (Visual Analogue Scale) score | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of dispersion of neurolytic agent around aorta is directly related to level of pain relief.Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactMohammed Moideen Chettiarthodi
IRCH, AIIMS, New Delhi
Outcome results
None listed