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Comparison of the effect of betamethasone gel versus lignocaine jelly for lubrication of the endotracheal tube on postoperative sorethroat,cough and hoarseness of voice and hence find a better agent to reduce the occurrence of postoperative airway complications thereby reducing morbidity

A randomized interventional prospective study on comparison of betamethasone gel versus lignocaine jelly applied on endotracheal tube to reduce the occurrence of postoperative airway complications in patients undergoing surgeries under general anesthesia at SMS medical college, during 2021-2023

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043377
Enrollment
100
Registered
2022-06-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: lignocaine jelly 2%: lubrication of the endotracheal tube before intubation Control Intervention1: Betamethasone gel 0.05%: lubrication of the endotracheal tube before intubation

Sponsors

Department of Anaesthesiology SMS Medical college and Attached Hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of ASA grade I and II 2.Patients undergoing elective surgery requiring endotracheal intubation (Duration less than 3 hours)

Exclusion criteria

Exclusion criteria: 1.Patients not willing to participate in the study 2.Surgeries of oral cavity and pharynx 3.Anticipated difficult airway 4.More than 2 attempts at intubation 5.Use of nasogastric or orogastric tube perioperatively 6.Patients with upper respiratory tract infection 7.Patients on steroids

Design outcomes

Primary

MeasureTime frame
Cases with postoperative sore throatTimepoint: 1,6,12 and 24 hours after extubation—

Secondary

MeasureTime frame
Cases with postoperative cough and hoarseness of voiceTimepoint: 1,6,12 and 24 hours after extubation;Hemodynamic parameters HR,SBP,DBP,MAPTimepoint: baseline,before intubation,after intubation every 5 min till 15 minutes,then every 15 min upto 120 minutes,at reversal of neuromuscular block,at the time of extubation,every 2 min till 8 minutes,then every 5 min upto 30 minutes;Occurrence of laryngospasm,bronchospasmTimepoint: during and after extubation—

Countries

India

Contacts

Public ContactDr Aparna Raj

SMS medical college and attached hospital

aiims.priyanka@gmail.com9309482150

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026