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To relieve post operative sore throat and cough after general anesthesia procedure

Effectiveness of Preemptive Dextromethorphan lozenges for post operative sore throat : A Randomised controlled study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043373
Enrollment
56
Registered
2022-06-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dextromethorphan lozenge: Dextromethorphan lozenge with a dose of 5mg administered orally 45minutes prior to procedure to check for post operative sore throat Control Intervention1: C

Sponsors

MADHURI G
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult patients between 18-60 yr of age of either sex. 2.ASA status I, II ,III Undergoing elective surgeries under general anesthesia with ETT tube in prone and supine position. 3.Patients posted for surgeries more than 1hr and lasting upto 6hrs

Exclusion criteria

Exclusion criteria: 1.Patients refusing to participate in the study 2.Patient posted for surgeries lasting more than 6hrs 3.Surgery involving the oral cavity, nasopharynx, larynx and neck regions. 4.History of preoperative sore throat, common cold, anticipated difficult airway. 5.Pregnant or lactating mothers. 6.Recent use of anti-inflammatory drugs 7.Allergic to study drug 8.On other centrally acting medications 9.Immune deficiencies 10.History of difficult intubation.

Design outcomes

Primary

MeasureTime frame
â?¢Assess the severity of post-operative sore throat in the study groupTimepoint: To assess severity at 1 , 6 and 24hours

Secondary

MeasureTime frame
â?¢To assess the degree of post-operative hoarseness of voice and coughTimepoint: To assess severity at 1 , 6 and 24 hours

Countries

India

Contacts

Public ContactDR MADHURI G

DR MGR UNIVERSITY

drsowmyamj80@gmail.com9880574092

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026