A study of Ropivacaine heavy and Bupivacaine heavy in hypertensive patients undergoing surgery under spinal anaesthesia

A comparative study of spinal anaesthesia with hyperbaric Ropivacaine 0.75% and hyperbaric Bupivacaine 0.5% in hypertensive patients undergoing lower abdominal surgery and lower limb surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/06/043360

Enrollment

Registered

2022-06-20

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I131- Hypertensive heart and chronic kidney disease without heart failure Health Condition 2: I131- Hypertensive heart and chronic kidney disease without heart failure Health Condition 3: I119- Hypertensive heart disease withoutheart failure Health Condition 4: I119- Hypertensive heart disease withoutheart failure

Interventions

Intervention1: spinal anaesthesia: comparison of spinal anaesthesia with hyperbaric Ropivacaine 0.75% and Bupivacaine 0.5% in patients with controlled hypertension undergoing lower abdominal and lowe

Eligibility

Inclusion criteria

Inclusion criteria: hypertensive patients, controlled blood pressure both male and female of age group 25- 70 years undergoing surgery under spinal anaesthesia .

Exclusion criteria

Exclusion criteria: 1. Patient refusal for procedure. 2. ASA grade > III, IV 3. Emergency Surgery 4. Immunocompromised patients 5. All contraindications for Regional anaesthesia 1. Those with bleeding disorders and local sepsis. 2. Those on anticoagulant and antiplatelet agent. 3. Those allergic to amide anaesthetics.

Design outcomes

Primary

Measure	Time frame
Heart rate, Blood pressure, mean arterial pressure recordingsTimepoint: 1min, 3min, 5min, 10min,15min,30min, 45min, 60 min intraoperative and postoperative period.	—

Secondary

Measure	Time frame
modified bromage score for motor block assessment, global patient satisfaction scale, and patient comfort scoreTimepoint: in the post operative period upto 3-4 hrs	—

Countries

India

Contacts

Public ContactAkrity Singh

IGIMS

drakrity_s@yahoo.co.in9431664293

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026