None listed
Conditions
Interventions
Intervention1: Injection Phenylephrine: single dose Injection Phenylephrine 1.5mg through intramuscular route 15 minutes before the administration of spinal anesthesia
Control Intervention1: Injection
Sponsors
SRM medical college hospital and Research centre
Eligibility
Inclusion criteria
Inclusion criteria: 1)singleton pregnancy at term posted for elective cesarean section 2)height from 150 cm to 180 cm 3)American Society of Anesthesiologists (ASA) II grade 4)BMI less than 40 kg/m2
Exclusion criteria
Exclusion criteria: 1) multiple pregnancy 2) contraindications for spinal anesthesia 3) parturients with comorbidities: gestational or nongestational hyptertension, eclampsia, etc. 4) preoperative history of bradycardia (heart rate (HR) less than 60 bpm 5) fetal complications: fetal macrosomia, fetal malformation, fetal distress in uterus, etc. 6) participants refused to sign informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraoperative Systolic Blood Pressure, Diastolic Blood Pressure, Mean arterial pressure, Heart rateTimepoint: At baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| neonatal outcomes: 1) UA blood gas analysis values: pH, base excess (BE), lactate, PaO2, PaCO2; 2) the incidence of fetal acidosis (UA pH 7.20)Timepoint: After baby delivery;Maternal outcomes: 1) the incidence of, nausea and vomiting; 3) time to first use of rescue phenylephrine after anaesthesia (completion of the subarachnoid injection will be defined as 0 time point) 4) Total number of rescue phenylephrine doses needed during surgery 5) Total number of rescue atropine needed during surgery 6)Adverse effects: bradycardia, hypertension, hypotension, nausea and vomitingTimepoint: At baseline | — |
Countries
India
Contacts
Public ContactChandrekanth
SRM Medical College Hospital and Research Centre
Outcome results
None listed