Health Condition 1: E611- Iron deficiency
Conditions
Interventions
Intervention1: Ferric carboxymaltose: Ferric carboxy maltose, 1gram in 100ml 0.9% NS for a period of 45 mins.
Sponsors
Bharat Institute of Technology
Eligibility
Inclusion criteria
Inclusion criteria: Patients who provide consent and present with NYHA II-III functional class due to stable symptomatic heart failure (HF) Left ventricular ejection fraction (LVEF) 40% or lower for patients in NYHA II and 45% or lower in NYHA III. Serum ferritin below 100 µg/L, or below 200 µg/L when transferrin saturation (TSAT) is below 20%
Exclusion criteria
Exclusion criteria: If the patient is not willing to provide consent. Known active infection, clinically significant bleeding, active malignancy. Chronic liver disease and/or screening alanine transaminase (ALT) or aspartate transaminase (AST) Anaemia due to reasons other than iron deficiency Immunosuppressive therapy or renal dialysis (current or planned within the next 6 months). History of erythropoietin, I.V or oral iron therapy, and blood transfusion in previous 12 weeks and/or such therapy planned within the next 6 months. Unstable angina pectoris as judged by the investigator, clinically significant uncorrected valvular disease or left ventricular outflow obstruction, obstructive cardiomyopathy, poorly controlled fast atrial fibrillation or flutter, poorly controlled symptomatic brady- or tachyarrhythmias. Acute myocardial infarction or acute coronary syndrome, transient ischaemic attack or stroke within the last 3 months. Coronary-artery bypass graft, percutaneous intervention (e.g. cardiac, cerebrovascular, aortic; diagnostic catheters are allowed) or major surgery, including thoracic and cardiac surgery, within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IMPROVEMENT IN HEMOGLOBINTimepoint: 3 Months | — |
Secondary
| Measure | Time frame |
|---|---|
| QUALITY OF LIFETimepoint: 3 months | — |
Countries
India
Contacts
Public ContactBavu Akhilkumar
Krishna Institute of Medical Sciences
Outcome results
None listed