Health Condition 1: E660- Obesity due to excess calories
Conditions
Interventions
Intervention1: TIME RESTRICTED FEEDING: Intervention Group
Intervention group consist of 2 arms-
• One arm consists of subjects who will be put on TRF (10:14).
Patient will be advised to consume the
Sponsors
ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Eligibility
Inclusion criteria
Inclusion criteria: Age 18-60 years Body Mass Index between 25-40 kg/m2 Willing to participate and assuring cooperation in the study
Exclusion criteria
Exclusion criteria: Known case or recently diagnosed diabetes mellitus Participants undergone any recent surgery Acute infection and advanced end organ damage History of pancreatitis Chronic liver disease, chronic heart disease and chronic kidney disease Pregnancy and lactation at the time of study Presence of zero positivity for Hepatitis B, Hepatitis C and Human Immunodeficiency Virus (HIV) Excessive smoking and alcohol use ( Currently enrolled or been a part of any weight loss program in last three months Intake of any anti-obesity drugs like orlistat, liraglutide, etc. currently or in the last three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight, Height, Circumferences and skinfolds Serum insulin, C-Reactive protein, ghrelin, cortisol, resistin, visfatin, asprosin, pentraxin-3, leptin, irisin, adiponectin, paraoxonase-1 (PON-1), cytokines, melatonin, circulating adipsin. Fasting blood glucose, Lipid profile, Complete Blood Count, Liver Function Test, Kidney Function Test, Oral Glucose Tolerance Test, Vitamin D, BIA and DEXA Scan Timepoint: At baseline, 6 weeks and 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Dietary Assessment Two-day dietary recall (one weekday and one weekend) along with validated Semi Quantitative Food Frequency Questionnaire. Energy Expenditure Global Physical Activity Questionnaire Indirect Calorimetry Metabolic Cart Technique Muscle strength Hydraulic Hand Grip Dynamometer Nutritional Chronotype Chrononutrition Profile – Questionnaire (CP-Q) Sleep Quality Pittsburgh Sleep Quality Index (PQSI) Quality of Life Short Form-36 questionnaire Timepoint: BASELINE, 1.5 MONTHS AND FINAL FOLLOW-UP | — |
Countries
India
Contacts
Public ContactDR NAVAL KISHORE VIKRAM
ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI
Outcome results
None listed