Comparison of steroid injection vs. sodium hyaluronate injection in the treatment of frozen shoulder

Comparative efficacy of Single Intra-articular injection of Triamcinolone acetonide with Sodium Hyaluronate in Periarthritis Shoulder: A double blind study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/06/043307

Enrollment

Registered

2022-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M958- Other specified acquired deformities of musculoskeletal system

Interventions

Intervention1: Triamcinolone Acetonide: Triamcinolone Acetonide 40mg single injection in shoulder joint intraarticularly Control Intervention1: Sodium Hyaluronate: Sodium Hyaluronate 30mg single injec

Eligibility

Inclusion criteria

Inclusion criteria: Age over 18 years At least three month old shoulder pain Significant restriction of ROM affecting the activities of daily life. Normal Antero-posterior Radiograph of Glenohumeral Joint Willingness to participate in study (Informed Written Consent) Willingness to forego any other concomitant treatment modality for Periarthritis shoulder

Exclusion criteria

Exclusion criteria: Unwillingness to participate in the study or drop out in the middle of the study. Intrinsic Gleno-humeral Pathology (glenohumeral tuberculosis, Malignancy, glenohumeral arthritis, etc.) History of substantial shoulder trauma History of surgery, dislocation, or fracture in the shoulder Clinical evidence of Complex Regional Pain Syndrome on Budapest criteria. History of Injection in the involved shoulder during the preceding 6 months or use of NSAIDs in last 7 days Abnormal Blood Count such as increased total count Use of antiplatelet medication â?? H/O coronary artery disease. Chronic Diseases (Rheumatoid Arthritis, Uncontrolled Diabetes Mellitus, Peripheral Vascular Disease, Gout, Clotting disorders) Localized Skin Disease/Pathology at the injection site. Pregnancy/Breastfeeding

Design outcomes

Primary

Measure	Time frame
To assess and compare the improvement in pain intensity (on the basis of Visual Analogue Score)Timepoint: At three, six and twelve weeks post injection	—

Secondary

Measure	Time frame
To compare the improvement in Range of Motion of Shoulder Joint in all planes between two groups at three, six- and twelve-weeks post injection. To assess and compare the improvement in function (on the basis of Shoulder Pain and Disability Index) between two groups at three, six- and twelve-weeks post injection. To assess and compare the improvement in quality of life (on the basis of 36 â?? Item Short Form Survey) between two groups at three, six- and twelve-weeks post injection Timepoint: At three, six- and twelve-weeks post injection	—

Measure

Time frame

To compare the improvement in Range of Motion of Shoulder Joint in all planes between two groups at three, six- and twelve-weeks post injection. To assess and compare the improvement in function (on the basis of Shoulder Pain and Disability Index) between two groups at three, six- and twelve-weeks post injection. To assess and compare the improvement in quality of life (on the basis of 36 â?? Item Short Form Survey) between two groups at three, six- and twelve-weeks post injection Timepoint: At three, six- and twelve-weeks post injection

—

Countries

India

Contacts

Public ContactDr Swapnil Sonune

AIIMS Bhopal

kothari_sy@yahoo.com9406720172

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026