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To compare efficacy and safety of hyperbaric ropivacaine with hyperbaric bupivacaine for spinal anesthesia in patients undergoing lower limb orthopedic surgeries

Hyperbaric 0.75% Ropivacaine versus hyperbaric 0.5% Bupivacaine for spinal anesthesia in adults undergoing lower limb orthopedic surgeries - BUPROP

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043286
Enrollment
70
Registered
2022-06-15
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 7- Osteopathic

Interventions

Intervention1: Spinal anesthesia: Spinal anesthesia is one of the commonest anesthetic procedures. It is a neuraxial anesthesia technique in which local anesthetic is placed directly in the intratheca

Sponsors

Government medical college haldwani
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Males or females 1. 18-70 years of age 2. American society of anesthesiologists (ASA) grade 1 or 2 3. Orthopedic lower limb surgeries 4. Under Spinal anesthesia

Exclusion criteria

Exclusion criteria: 1.Patients not in the desired age group 2.ASA grade >2 3.Coagulopathy 4.Patients with known allergy to study drugs 5.Patient refusal for spinal anesthesia 6.Patient who require epidural along with spinal anesthesia 7.Patient requiring conversion of spinal to general anesthesia 8.Expected duration of surgery more than 3 hours

Design outcomes

Primary

MeasureTime frame
To compare the time taken to achieve and total duration of adequate sensory blockade (level of block upto T10) achieved in spinal anesthesia with hyperbaric 0.75% Ropivacaine and hyperbaric 0.5% Bupivacaine in patients undergoing lower limb orthopedic surgeries. Timepoint: Before onset and after completion of surgery

Secondary

MeasureTime frame
To compare both the study groups for time for first analgesic demand postoperatively. Timepoint: After surgery whenever patient complains pain;To compare the motor block achieved with both the study drugs and time taken for full regression of the motor blockTimepoint: Before start and completion of surgery

Countries

India

Contacts

Public ContactShailesh Lohani

Government medical college haldwani

drshaileshlohani@gmail.com07088973697

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026