A clinical trial to compare the effects of 0.5% Ropivacaine with 1mL (0.3mg) Buprenorphine versus 0.5% Ropivacaine with 1mL Normal saline while giving Supraclavicular brachial plexus block for upper limb orthopaedic surgeries.

Buprenorphine as an adjuvant to 0.5% Ropivacaine for supraclavicular brachial plexus block: A randomized, prospective study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/06/043277

Enrollment

Registered

2022-06-15

Start date

Unknown

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: INJECTION BUPRENORPHINE WITH 0.5% ROPIVACAINE: Injection Buprenorphine 1ml (0.3mg) with 30 ml 0.5% Ropivacaine for supraclavicular brachial plexus block. Intervention2: Injection Bupren

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiology(ASA) physical status I and II. 2.Scheduled for elective Orthopaedic upper limb surgery under supraclavicular brachial plexus block. 3. Informed and written consent.

Exclusion criteria

Exclusion criteria: 1.Unwilling patients. 2.Patients belonging to ASA physical status III or more. 3. Patients with known hypersensitivity to local anaesthetics. 4.Infection at the site of block. 5.Patients with known coagulopathy or patients on anticoagulation therapy.

Design outcomes

Primary

Measure	Time frame
To evaluate the duration of post operative analgesia by addition of injection buprenorphine to 0.5% Ropivacaine solution.Timepoint: After completion of the block to next 24hours.	—

Secondary

Measure	Time frame
1.Sensory block onset time. 2.Motor block onset time. 3.Post operative analgesia 4.Duration of motor block 5.Side effects and complicationsTimepoint: Sensory and Motor block onset time to be assessed for 30mins after completion of the block. Motor block duration and post operative analgesia to be assessed for 24hours after completion of the block.	—

Countries

India

Contacts

Public ContactDr Hiranya Kumar Saharia

Gauhati Medical College and Hospital, Guwahati

sahariahiranya@gmail.com9435087643

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026