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Evaluation of effects of methylprednisolone injection in masseter muscle versus deltoid muscle after wisdom tooth removal

Efficacy of Methylprednisolone Administration into Masseter Muscle versus Deltoid Muscle on Postoperative Sequelae in Minor Oral Surgery: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043230
Enrollment
70
Registered
2022-06-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Inj. Methylprednisolone 40 mg Intramasseter administration: preoperatively after achieving adequate anesthesia Inj. Methylprednisolone 40mg Intramasseter administration. Control Interve

Sponsors

The Director
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Partially or completely bony/soft tissue impacted mandibular third molars. 2. Age group 20-40 years.

Exclusion criteria

Exclusion criteria: 1. Acute infection of odontogenic and non-odontogenic causes. 2. Pregnant and lactating females. 3. Patients with known systemic disorder such as diabetes mellitus, hypertension, thyroid disorder, immunocompromised state etc.

Design outcomes

Primary

MeasureTime frame
1. Comparison of mean pain intensity scores of group 1 and group 2 as assessed by visual analogue scale. 2. Comparison of facial edema as assessed by mean distance between : Tragus and lip commissure, tragus and soft tissue pogonion, gonion and external canthus of eye of group 1 and group 2. 3. Comparison of mean values of maximum interincisal opening of group 1 and group 2.Timepoint: Preoperatively on the day zero (day of surgery) and on the first, third, and seventh post-operative days.

Secondary

MeasureTime frame
1. Comparison of mean scores of wound healing of group 1 and group 2 as assessed by healing index by Landry et al. 2. Comparison of total number of postoperative analgesics taken for group 1 and group 2. Timepoint: On the first, third, and seventh post-operative days.

Countries

India

Contacts

Public ContactDr Madhuri Shinde

Lady Hardinge Medical College

amarjeetgambhir@gmail.com8427543060

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026