Health Condition 1: F40-F48- Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders
Conditions
Interventions
Intervention1: Inhibitory Learning-based Exposure Response Prevention Therapy for patients with Obsessive-Compulsive Disorder.: 12 - 16 number of sessions with a duration of 1 hour for each session an
Sponsors
Mareena Thampy
Eligibility
Inclusion criteria
Inclusion criteria: 1. Primary diagnosis of OCD as per DMS 5. 2. Patients aged 18 -50 years 3. Y-BOCS score of 16 or greater 4. Education level of minimum class VII. 5. Stabilized on medication for 8 weeks prior to entry into the study. 6. Working knowledge of English or Malayalam language
Exclusion criteria
Exclusion criteria: 1. History suggestive of head injury, neurological/neurosurgical illnesses, 2. A primary diagnosis of, schizophrenia or psychosis, schizoaffective disorder, bipolar disorder with current episode mania/ severe depressive episode, current substance use/substance dependence except for Nicotine Use/Dependence, clinical evidence of intellectual disability. 3. Participants who have undergone more than 6 sessions of structured ERP, CBT, Mindfulness-based CBT, or Metacognitive therapy with ERP in the previous 3 months. 4. People with medical conditions that may be a contraindication for exposure therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom severity of OCD as measured by YBOCS symptom severity and Clinical Global Impression Scale (CGI).Timepoint: Baseline 14 weeks (post) 12 weeks after post (1st follow up) 24 weeks after post (2nd Follow up will be attempted) | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity of anxiety (HAM-A)Timepoint: Pre-intervention, post-intervention and follow up;The severity of depression as measured by (HAM-D)Timepoint: Pre-intervention, post-intervention and follow up | — |
Countries
India
Contacts
Public ContactMareena Thampy
National Institute of Mental Health and Neurosciences
Outcome results
None listed