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Comparative evaluation of pain relieving effects of 2 doses of Dexamethasone given along with Bupivacaine during surgery

Comparison of analgesic effect of different doses of Dexamethasone as an adjuvant to Bupivacaine in ultrasound guided supraclavicular brachial plexus block.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043190
Enrollment
36
Registered
2022-06-13
Start date
Unknown
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Prospective, observational, randomised comparative double blinded study. 3 groups- group D4, D8 and B: there are three groups in this study group D4 contains adjuvant dexamethasone 4mg

Sponsors

School of medical sciences and research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 & 2 Ortho upper limb surgeries

Exclusion criteria

Exclusion criteria: Patient refusal to participate in study. History of allergy to local anesthetic and Dexamethasone. History of usage of corticosteroids, opioids and any other analgesics. Infection at the site of injection. Pregnant females. Coagulopathy or bleeding diathesis. Significant cognitive or psychiatric history. History of endocrine disease- Diabetes mellitus and thyroid disease History of CNS, cardiovascular and renal disease.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the duration of analgesic effect with two different doses Dexamethasone (8mg Vs 4 mg) as an adjuvant to Bupivacaine in supraclavicular brachial plexus block.Timepoint: assessment of pain will be done till 20 mins just after giving the block and then in postoperatively at 6 hrs,9 hrs, 12hrs and 24hrs.

Secondary

MeasureTime frame
To evaluate and compare the time required with respect to achieve: complete onset of sensory block complete onset of motor block (2) To observe the incidence of complications in 3 different groups. Timepoint: Assessment of duration of analgesia till 24 hrs

Countries

India

Contacts

Public ContactAnshil Bhatia

School of medical sciences and research

uttam.verma@sharda.ac.in9868378740

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026