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effect of locally delivered drug after extraction to control pain and infection without taking oral tablets

Efficacy of local drug delivery system in minimizing the systemic administration of postoperative medication

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043178
Enrollment
140
Registered
2022-06-10
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K049- Other and unspecified diseases ofpulp and periapical tissues

Interventions

Intervention1: medicated microspheres: Microspheres containing amoxicillin and clavulanic acid – 625 mg 2) Microspheres containing acelofenac – 100mg duration/ observation period is 3 days for acelof

Sponsors

chandra kiran Venkata sai pathuri
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and ASA 2 individuals between 20-60 years of age. Individuals tolerant to NSAID’s. Individuals with no known pencillin allergy

Exclusion criteria

Exclusion criteria: Patients who are on analgesics or sedatives for any other systemic issues Patients who are on antibiotics for any other systemic issues

Design outcomes

Primary

MeasureTime frame
pain - will be assessed by Numerical Rating Scale(NRS)Timepoint: 1st day, 2nd day and 3rd day—

Secondary

MeasureTime frame
comfort - will be assessed using comfort rating scaleTimepoint: 1st, 2nd and 3rd day;infection - will be assessed using Landry et al healing index by clinical examinationTimepoint: 7th day—

Countries

India

Contacts

Public ContactDr Chandra Kiran Venkata Sai Pathuri

sibar institute of dental sciences

drpckvsai@gmail.com7658900210

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026