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Dexmedetomidine versus propofol infusion for sedation during chemoport insertion

A Comparative Study Between Dexmedetomidine and Propofol Infusion for Monitored Anaesthesia Care during Internal Jugular Vein Chemoport Insertion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043177
Enrollment
50
Registered
2022-06-10
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Injection Propofol infusion: Inj. Propofol infusion started @ 125mcg/kg/min intravenously. Once OAAS score 3 is achieved, the infusion was reduced to 25-75 mcg/kg/min and titrated to ma

Sponsors

Rajiv Gandhi Cancer Institute and Research centre
Lead Sponsor
Rajiv Gandhi Cancer Institute and Research centre
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1)ASA grade I, II 2)Patient demanding anaesthesia services for chemoport insertion. 3)Internal jugular vein chemoport insertion

Exclusion criteria

Exclusion criteria: 1)BMI more than 35 2)Neuropsychiatric patients 3)On medications for chronic pain 4)History of CAD, arrhythmias, cardiac problems. 5)Asthmatics/COPD patients. 6)Liver dysfunction. 7)Chronic kidney disease. 8)Substance abuse.

Design outcomes

Primary

MeasureTime frame
Time to achieve observer�s assessment of alertness/sedation (OAAS) score of 3 with dexmedetomidine and propofol infusion.Timepoint: 0 min ,5 min,10 min,15 min,20 min, 25 min,30 min,35 min,40 min,45 min,50 min.

Secondary

MeasureTime frame
a)Maintaining OAAS score of 3 throughout the procedure. b)To assess the amount of rescue sedation used in both groups. c)To assess the satisfaction score of surgeon, anaesthesiologist and patient. d)Haemodynamic stability assessment. e)Post-operative discharge score assessment. f)Bispectral index assessment at OASS score of 3. Timepoint: 0 min ,5 min,10 min,15 min,20 min, 25 min,30 min,35 min,40 min,45 min,50 min.

Countries

India

Contacts

Public ContactDr NITESH GOEL

Rajiv Gandhi Cancer Institute & Research centre

drniteshgoel@gmail.com09717773292

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026