Health Condition 1: H350- Background retinopathy and retinalvascular changes
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Able to complete adequate or reliable image acquisitions in one or both eyes. 2) Diagnosis of Primary Open Angle Glaucoma (POAG) or Primary Angle Closure Glaucoma (PACG) based on IOP, Fundus photographs or OCT scans changes showing Notch, Rim loss, Disc hemorrhage, Nerve Fiber Layer defect, Peripapillary atrophy and Visual Field defects. 3) Diagnosis of retinal pathologies (DR, AMD, vascular occlusions, macular hole, epiretinal membrane, retinal detachment, hypertensive retinopathy, disc edema, posterior uveitis) based on structural changes seen in Fundus or Ultra widefield fundus photographs or OCT or OCTA.
Exclusion criteria
Exclusion criteria: 1) History of trauma or injury to the eye/ symptomatic inflamed eyes 2) Significant media opacity that precludes acquisition of images. 3) Any physical disability which will preclude the patients from performing necessary study investigations 4) Pregnant and Nursing women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Successful enrollment of participants and prospective collection ocular images, clinical exam findings and blood tests providing a robust ground truth to train and validate a deep learning algorithm that can identify novel signals - for example systemic disease - and detect or predict progression of ocular pathologies identified in the studyTimepoint: 24 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To identify novel signals in retinal imaging that may predict early signs of glaucoma, retinal pathology as well as its systemic associationTimepoint: 24 months | — |
Countries
India
Contacts
Aravind Eye Hospital and Postgraduate Institute of Ophthalmology