Role of intravenous calcium as preventing of post spinal hypotension among pre-eclamptic women undergoing caesarean delivery and patient and fetal outcome

Role of prophylactic intravenous calcium in prevention of post spinal hypotension among women with pre-eclampsia undergoing caesarean delivery: a placebo controlled randomised clinical trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/06/043149

Enrollment

100

Registered

2022-06-10

Start date

Unknown

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O140- Mild to moderate pre-eclampsia Health Condition 2: O140- Mild to moderate pre-eclampsia Health Condition 3: O140- Mild to moderate pre-eclampsia

Interventions

Intervention1: jipmer drug supply: HINDUSTAN MEDICINE PVT LTD. Intervention2: INTRAVENOUS CALCIUM: INTRAVENOUS CALCIUM 500 mg Before the spinal anesthesia, single dose Control Intervention1: INTRAVENO

Eligibility

Inclusion criteria

Inclusion criteria: Preeclamptic patient in age group of 18 - 50 years those who are on magnessium sulphate supplementation undergoing cesarean delivery under spinal anesthesia.

Exclusion criteria

Exclusion criteria: 1.NICE I category of cesarean delivery. 2. Abnormal placentation. 3. Cesarean delivery under general anesthesia.

Design outcomes

Primary

Measure	Time frame
To compare the incidence of post spinal hypotension after prophylactic intravenous calcium administration in preeclamptic women receiving intravenous magnesium.Timepoint: Duriung the procedure after spinal anaesthesia (Baseline)	—

Secondary

Measure	Time frame
To compare the effect of prophylactic intravenous calcium administration on post-partum blood loss in patient undergoing cesarean delivery under spinal anaesthesia. Blood loss is calculated after the suturing of uterus is completed. 2. To compare the effects of prophylactic intravenous calcium administration on composite of neonatal outcome, APGAR score 1 min and 5 min , NICU admission after the delivery of baby and umbilical arterial ph after the delivery of baby.Timepoint: Baseline	—

Measure

Time frame

To compare the effect of prophylactic intravenous calcium administration on post-partum blood loss in patient undergoing cesarean delivery under spinal anaesthesia. Blood loss is calculated after the suturing of uterus is completed. 2. To compare the effects of prophylactic intravenous calcium administration on composite of neonatal outcome, APGAR score 1 min and 5 min , NICU admission after the delivery of baby and umbilical arterial ph after the delivery of baby.Timepoint: Baseline

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Countries

India

Contacts

Public ContactNavin Kumar Yadav

JIPMER

navinychapur6@gmail.com8438818827

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026