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two different drugs have given for reduce pain due to propofol injection.

Comparative study of intravenous lignocaine hydrochloride and dexamethasone sodium phosphate in reduction of propofol induced vascular pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043137
Enrollment
100
Registered
2022-06-09
Start date
Unknown
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Inj. Dexamethasone sodium phosphate: 12mg (3cc) Intravenous injection to be given over 10 second and wait for 2 minutes before injecting propofol 2mg/kg Control Intervention2: I

Sponsors

Health and family welfare department
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I ,II Patient aged 18 to 60 yrs, either sex Patients scheduled for planned surgeries Consent

Exclusion criteria

Exclusion criteria: ASA III, IV and V Age 60 yrs Parents refusing to give consent Patinets having pre-existing cardiac,neurological and respiratory diseases Local infection/inflammation at Intracath site Emergency Surgeries Known hypersensitivity to either of the study drug (Lignocaine or Dexamethasone) Patients having communication problems Psychiatric illness CNS or neuromuscular disorders Patient taking pain killers chronically or sedatrives preoperatively H/O drug abuse or alcoholic Patients requires repid sequence induction Allergic to drugs Patients having difficult IV access and small caliber veins Pregnant and lactating females

Design outcomes

Secondary

MeasureTime frame
Skin itching, Rashes any other signs of adverse drug reactionsTimepoint: 24 hours

Primary

MeasureTime frame
Assessment of pain response during injecting PropofolTimepoint: Spontaneous complaints of pain and behavioral signs which included facial grimace, arm withdrawal, vocal and verbal rating score were recorded at 15 sec., 30 sec., 45 sec., and 60 sec.

Countries

India

Contacts

Public ContactDr Nilesh Solanki

B.J.Medical college Ahmedabad

nmscbaps@gmail.com9998991716

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026