Skip to content

Study comparing the effect of a numbing medicine lignocaine compared to pain killer fentanyl, on the time taken to recover from effect of muscle paralysis agent given during anesthesia in non-emegency surgery in children.

Effect of single-dose intravenous lignocaine versus fentanyl on neuromuscular recovery time after general anaesthesia in elective paediatric surgery: a randomized controlled pilot study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043111
Enrollment
40
Registered
2022-06-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q639- Congenital malformation of kidney,unspecified Health Condition 2: Q431- Hirschsprungs disease Health Condition 3: Q549- Hypospadias, unspecified Health Condition 4: 4- Measurement and Monitoring Health Condition 5: O- Medical and Surgical Health Condition 6: Q445- Other congenital malformations ofbile ducts Health Condition 7: N508- Other specified disorders of malegenital organs Health Condition 8: Q539- Undescended testicle, unspecified Health Condition 9: K409- Unila

Interventions

Intervention1: Intravenous Lignocaine: Intravenous Lignocaine (1.5 mg/kg), given just prior to reversal of neuromuscular blockade to decrease the stress of extubation and avoid respiratory/ airway com

Sponsors

Mridul Dhar
Lead Sponsor
Dr Yashwant Singh Payal
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA- I-II Patients undergoing surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1. Patients with known allergy to amide local anaesthetics 2. Patients with known seizure disorder 3. Known or expected difficult airway 4. Renal, hepatic or muscular disorders 5. Patients taking drugs affecting neuromuscular function

Design outcomes

Primary

MeasureTime frame
1. Time from giving reversal and achieving TOF of 0.9 2.Time from giving reversal to extubating the trachea Timepoint: Every 12 seconds, from giving reversal to reaching TOF of 0.9

Secondary

MeasureTime frame
1. Any incidence of coughing, bucking, post-extubation laryngospasm, bronchospasm, hypoxemia, nausea, vomiting 2. Heart rate and BP will be recorded just after extubating the trachea and 5 minutes after extubation 3. TOF ratio at the time of clinical adequacy of extubationTimepoint: 1. Complications: Just after extubation to post op PACU 2. HR and BP, after extubation and 5 mins after

Countries

India

Contacts

Public ContactMridul Dhar

All India Institute of Medical Sciences

mriduldhar@hotmail.com9717778374

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026