Skip to content

Dexmedetomidine comparison with Labetalol for induced hypotension during functional endoscopic sinus surgery

Dexmedetomidine versus Labetalol for induced hypotension during functional endoscopic sinus surgery: A randomized, double-blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043087
Enrollment
60
Registered
2022-06-08
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: FUNCTIONAL ENDOSCOPIC SINUS SURGERY: Group L IV labetalol 0.4 mg/kg intravenously as loading dose after diluting with 50 mL of 0.9 percent normal saline followed by an infusion of 0.04

Sponsors

Government Institute Of Medical Sciences
Lead Sponsor
GOVERNMENT INSTITUTE OF MEDICAL SCIENCES
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status I–II and age between 20 and 60 years patients scheduled for elective FESS under general anesthesia.

Exclusion criteria

Exclusion criteria: age = 20 years known allergy to the anesthetic agents patients with compromised renal hepatic and cardiac function hypertension coagulation disorders or patients on medications affecting coagulation system

Design outcomes

Secondary

MeasureTime frame
To assess the quality of the surgical field, adverse effects and recovery characteristics Timepoint: After FESS Visual Analogue Scale score seen after every 15 minutes till score is more than 4

Primary

MeasureTime frame
To compare the time to achieve the target MAP with infusion doses of study drugs.Timepoint: MAP will be recorded before starting the bolus and infusion of the study drug (baseline measurement, one minute after endotracheal intubation, and then every 15 minutes throughout the procedure)

Countries

India

Contacts

Public ContactDr Savita Gupta

Government Institute Of Medical Sciences

dr.gsavita@gmail.com8750657382

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026