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A study to compare duration of pain relief between dexmedetomidine or clonidine in combination with lignocaine with adrenaline in local anaesthesia in tympanoplasty

Comparison of dexmedetomidine and clonidine as an adjuvant to lignocaine with adrenaline in infiltration anaesthesia in tympanoplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043057
Enrollment
60
Registered
2022-06-07
Start date
Unknown
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H728- Other perforations of tympanic membrane

Interventions

Intervention1: Dexmedetomidine with lignocaine and Adrenaline: Post auricular region and four quadrants of external auditory canal are locally infiltreted with 12 ml of lignocaine 2% with 1 in 200000

Sponsors

JLN medical college Ajmer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) age group 18-60 years. 2) body weight 40-60 kg. 3)patient belonging to ASA(American society of anaesthesiology) class 1 and 2. 4)patient undergoing elective tympanoplasty under local anaesthesia. 5)duration of surgery 60 mins.

Exclusion criteria

Exclusion criteria: 1) Age 60 years. 2) ASA grade III and above. 3) Patients allergic to study drugs. 4) History of use of any opioids or sedative medications in the week prior to surgery 5) Patients on psychotropic drug. 6)Pregnant and lactating females. 7)Patients with cardiovascular disease and congenital disorders. 8)Significant systemic disorders. 9) Patient with history of seizure disorders 10)Patient refusal to take part in study 11) Obese patients with BMI more > 28 kg/m2 .

Design outcomes

Primary

MeasureTime frame
comparison of duration of analgesia in both the group for 24 hoursTimepoint: comparison of onset of analgesia ( in seconds) and duration of analgesia during total duration of surgery and for 24 hours

Secondary

MeasureTime frame
To assess and compare the hemodynamic changes. bleeding at the site of surgery. patient and surgeon satisfaction. Timepoint: around 1 year

Countries

India

Contacts

Public ContactDr Kavita Jain

JLN medical college Ajmer

drkavitajain15@gmail.com9414006151

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026