Health Condition 1: H160- Corneal ulcer
Conditions
Interventions
Intervention1: Topical corticosteroids: Topical corticosteroids will be added along with the anfungus first day after the transplant done for fungal keratities.
Both the groups will receive topical Na
Sponsors
L V Prasad Eye Institute
Eligibility
Inclusion criteria
Inclusion criteria: 1.Cases with microbiologically confirmed fungal keratitis undergoing therapeutic keratoplasty for worsening of infection. 2.Size of infiltrate less or equal to 10 mm. 3.Intraoperative no evidence of residual infection 4.Immediate Post operative anterior chamber formed and no clinical evidence of infection 5.Use of MK medium corneal tissue of any grade with or with out intact epithelium 6.Intraoperative Preserved lens 7.Ready to give consent 8.Consent for regular follow-up 9.More than 18 years 10.Surgery performed by surgeons with experience of performing more than 20 TPK.
Exclusion criteria
Exclusion criteria: 1.Any evidence of intraop or clinical post-operative infection 2.Size of infiltrate > 10 mm 3.Not willing to come for regular follow-up or admission or giving consent 4.Disorganized anterior chamber 5.Posterior segment involvement as confirmed on Echoes in the posterior segment on B scan 6.Intraoperative presence of retero-iris and lens exudates. 7.Presence if corneal perforation before the surgery 8.Presence of uncontrolled diabetes or any other cause of decreased imununity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Graft survival rate at 6 months in both the groups and compared.Timepoint: 3, 7,14, 30 days, 3 , 6 months and 1 year of follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of patients having recurrence of similar infection with in 2 weeks of surgery.Timepoint: 3, 7,14, 30 days, 3 , 6 months and 1 year of follow-up | — |
Countries
India
Contacts
Public ContactDrBhupesh Bagga
L V Prasad Eye Institute
Outcome results
None listed