To calculate apprpriate dose of Bupivacaine give in spinal anaesthesia for Caesarean Delivery for preventing fall in blood pressure during the operation

Height Adjusted Dose versus Height and Weight-Adjusted Dose of Intrathecal Hyperbaric Bupivacaine for Caesarean Delivery in prevention of Maternal hypotension: A Prospective, Double-Blinded Randomised Study

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/06/043001

Enrollment

Registered

2022-06-03

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O367- Maternal care for viable fetus inabdominal pregnancy

Interventions

Intervention1: Inj Bupivacaine heavy 0.5% intrathecal route: Dose depends on each group Group H- Dose of drug depends on height of the patient on basis of height chart Control Intervention1: Inj Bupi

Eligibility

Inclusion criteria

Inclusion criteria: 1.Term gestation > 37 weeks 2.Elective Caesarean Section 3.Age > 18 to 40 years 4.Weight 50 to 110 kg 5.Singleton pregnancy 6.Height 150- 180 cms 7.ASA I and II

Exclusion criteria

Exclusion criteria: 1.Absolute contraindication to neuraxial anaesthesia 2.ASA III and IV 3.PIH 4.Cardiorespiratory problems 5.Gestation or pre-existing Diabetes 6.Weight 110 kg 7.Height 180 cms 8.IUGR and Fetal abnormalities 9.Patient not willing to participate in the study

Design outcomes

Primary

Measure	Time frame
1.To determine the incidence of maternal hypotension in Height adjusted and height and weight adjusted dosing regimensTimepoint: Baseline and every 5 minutes upto 90 minutes after giving spinal anaesthesia with bupivacaine	—

Secondary

Measure	Time frame
1. Time taken to attain sensory level upto T6 in both group 2. Time taken to attain complete motor block( Modified bromage scale 1) in both group 3. Dose of Ephedrine needed in both group. 4. Incidence of complication in both group. 5. Neonatal APGAR Score at 1 and 5 min. Timepoint: 2 hours	—

Countries

India

Contacts

Public ContactDr Manasa M

Rajarajeswari Medical College and Hospital, Bengaluru

jokiran2009@gmail.com07726899533

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026