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Evaluation of Salivary Matrixmetalloproteinase-8 levels when ozonated olive oil gel is used as an adjunct to non surgical periodontal therapy

Evaluation of Salivary Matrixmetalloproteinase-8 levels in chronic periodontitis patients treated with ozonated olive oil gel as an adjunct to non surgical periodontal therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/042993
Enrollment
40
Registered
2022-06-03
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: application of ozonated olive oil gel: ozonated olive oil gel is applied in chronic periodontitis patients after non surgical periodontal therapy in test group Intervention2: ozonated o

Sponsors

Samhitha Kothapalli
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age group 25-55 years. 2. Subjects who are apparently healthy. 3. Probing pocket depth and clinical attachment level of =5mm. 4. Radiographic evidence of horizontal bone loss. 5. Patients who gave informed consent for the study.

Exclusion criteria

Exclusion criteria: 1. Radiographic evidence of vertical boneloss 2. Patients who has history of drug allergy. 3. Any form of tobacco consumption. 4. Pregnancy or lactating females. 5. History of any form of periodontal therapy in the past 1 year.

Design outcomes

Primary

MeasureTime frame
To evaluate salivary MMP-8 and periodontal parameters at baseline and 3 months after NSPT with ozonated olive oil gel application. 2. To evaluate salivary MMP-8 levels and periodontal parameters at baseline and 3 months after NSPT with placebo gel application. Timepoint: baseline and 3 months—

Secondary

MeasureTime frame
To evaluate salivary MMP-8 and periodontal parameters at baseline and 3 months after NSPT with ozonated olive oil gel application. 2. To evaluate salivary MMP-8 levels and periodontal parameters at baseline and 3 months after NSPT with placebo gel application. Timepoint: baseline and 3 months—

Countries

India

Contacts

Public ContactSamhitha Kothapalli

Sibar Institute Dental Sciences

kishoreuga@yahoo.co.in9000534590

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026