Health Condition 1: K047- Periapical abscess without sinus
Conditions
Interventions
Intervention1: Simvastatin: 1.2% Simvastatin Gel was prepared by coacervation-phase separation method.10 mg of Simvastatin was dissolved in 2.5 ml of ethanol. Carbopol P was used for preparing hydroge
Sponsors
Uma Bharathy R
Eligibility
Inclusion criteria
Inclusion criteria: Patients between 20-40 years of age from both the gender, Periapical lesions involving maxillary and mandibular incisors of strictly endodontic origin, The diameter of the bone defect of 10 -20 mm, Patients willing for voluntary participation & have signed informed consent, Patients with good oral hygiene, Systemically healthy patients.
Exclusion criteria
Exclusion criteria: Periodontally compromised teeth with poor prognosis, Tooth with pathosis associated with vertical root fracture, Patients with bleeding disorders, Platelet count <1, 50, 000/mm3, Patients showing unacceptable oral hygiene maintenance, Patients with use of tobacco or tobacco related products, Pregnant / Lactating patients, Patients with known systemic diseases, Patients with any known allergies, Patients with any known metabolic disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absence of swelling, pain, pus discharge, sinus opening, Mobility, Tenderness to percussionTimepoint: 1,3,6,9 and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone density evaluation of the Periapical region was done after surgery using CBCTTimepoint: 6 and 12 months | — |
Countries
India
Contacts
Public ContactDr Uma Bharathy
Tamilnadu Government Dental College and Hospital
Outcome results
None listed