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use of resveratrol in periodontitis and diabetes

Effect of resveratrol usage as an adjunct to scaling and root planning in Type II Diabetic patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/05/042806
Enrollment
30
Registered
2022-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: systemic administration of resveratrol: 150mg 1 tablet daily for 30 days Control Intervention1: Resveratrol capsule systemic administration and placebo: Resveratrol is a polyphenol stil

Sponsors

katamneni poojitha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with moderately controlled diabetes mellitus (HbA1c 6-7) patients with generalized pocket depth of 5- 6 mm and CAL � 5mm. Patients having atleast 20 permanent teeth. Should not have undergone any form of dental treatment

Exclusion criteria

Exclusion criteria: 1. Patients with any systemic disease other than diabetes. 2. Habit of smoking 3. Pregnancy or lactation 4. Used antibiotics /or anti- inflammatory drugs in the last 3 months.

Design outcomes

Primary

MeasureTime frame
Periodontal therapy proved to be effective in reducing the inflammatory state and oxidative stress, as well as improving the glycemic control in diabetic patients. The present study is planned to observe the benefits of systemic administration of resveratrol in chronic periodontitis patients with type II diabetes before and after scaling and rootplaning. Parameters were recorded at baseline, 7 weeks postoperative. Primary outcome parameters assessed were HbA1C, Probing pocket depth (PPD) and Clinical attachment level (CAL).Timepoint: Baseline 7 weeks post operative

Secondary

MeasureTime frame
plaque index(PI), Modified sulcular bleeding index(MSBI) as secondary outcome parameters.Timepoint: Baseline 7 weeks post operative

Countries

India

Contacts

Public Contactkatamneni poojitha

sibar institute of dental sciences

kishoreuga@yahoo.co.in9000534590

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026