THE ROLE OF INDOCYANINE GREEN FLUORESCENCE IMAGING IN OESOPHAGEAL CANCER SURGERIES TO ASSESS ANASTOMOTIC SITES DURING SURGERY

THE ROLE OF INDOCYANINE GREEN FLUORESCENCE IMAGING FOR INTRAOPERATIVE ASSESSMENT OF GASTRIC OR COLONIC CONDUIT PERFUSION IN OESOPHAGEAL CANCER SURGERIES- A PILOT STUDY

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2022/05/042805

Enrollment

Registered

2022-05-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C159- Malignant neoplasm of esophagus, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age – 18-85 years 2.Biopsy proven cancers of oesophagus involving the middle, distal 1/3rd and GE junction tumors planned for Curative Resection procedures (Ivor Lewis oesophagectomy/McKeown oesophagectomy/Orringer oesophagectomy) 3.Patient fit for major surgery

Exclusion criteria

Exclusion criteria: 1.Recurrent oesophageal cancers 2.Non resectable cancers 3.Any past history of extensive surgery in the mediastinum, neck or stomach which might have resulted in the disruption of arteriovenous and lymphatic system. 4.Patient not fit for surgery 5.Metastatic carcinoma oesophagus 6.Patients not giving consent for participation in this study

Design outcomes

Primary

Measure	Time frame
To determine the anastomotic leak rates after intraoperative perfusion assessment of gastric or colonic conduits with ICG dye Timepoint: Immediately after surgery till 5th post operative day	—

Secondary

Measure	Time frame
2. Establishing the ideal time for intraoperative assessment of vascularity after injection of ICG dyeTimepoint: Intraoperative assessment;2. To determine the difference in qualitative assessment of gastric/colonic conduit vascularity by visual inspection and by ICG fluorescence imagingTimepoint: Intraoperative assessment;To assess the conduit margin revision rates with ICG fluorescence imaging at the proposed anastomotic site compared to visual assessment.Timepoint: Intraoperative assessment	—

Measure

Time frame

2. Establishing the ideal time for intraoperative assessment of vascularity after injection of ICG dyeTimepoint: Intraoperative assessment;2. To determine the difference in qualitative assessment of gastric/colonic conduit vascularity by visual inspection and by ICG fluorescence imagingTimepoint: Intraoperative assessment;To assess the conduit margin revision rates with ICG fluorescence imaging at the proposed anastomotic site compared to visual assessment.Timepoint: Intraoperative assessment

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Countries

India

Contacts

Public ContactHaraesh Maranna

Dr BRA Institute of Rotary Cancer Hospital, All India Institute of Medical Sciences

dr_sunilk@hotmail.com9968300241

Outcome results