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To study how measurements of volumes inside the lungs at the end of expiration also known as end expiratory lung volumes , by using specialized techniques, may help in titrating pressures in the lungs during expiration also known as positive end expiratory pressures

Role of measurement of End Expiratory Lung Volume during titration of Positive End Expiratory Pressure in children

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/05/042802
Enrollment
30
Registered
2022-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Measurement of End expiratory Lung Volume at different PEEP using  E-sCOVX module on GEcarescape R860 ventilator: •The mechanical ventilators used will be GE CARESCAPE R860. Sof

Sponsors

Dr Farhan Shaikh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Invasively ventilated children weighing 8-kg or more until the age of 18-years.

Exclusion criteria

Exclusion criteria: • Children on NIV • Children who are hemodynamically unstable for data collection. • Children who are already on High Frequency Oscillatory ventilation. • Children with significant Patient Ventilator Asynchrony • Children with open chest (following surgery) • Children with air leaks, with chest Drains • Children with raised Intra cranial pressure

Design outcomes

Primary

MeasureTime frame
To compare PEEP titrated by traditional bedside method with the PEEP titrated using End Expiratory Lung Volume (EELV) measurement made by Nitrogen wash out technique in pediatric ventilated patients Timepoint: 30 minutes, each mode—

Secondary

MeasureTime frame
To study how the end expiratory lung volumes measured at different positive end expiratory pressures can be used for measurement of lung compliances and transpulmonary pressures in different lung pathologies in children Timepoint: 30 mins, each mode—

Countries

India

Contacts

Public ContactDr Farhan Shaikh

Rainbow childrens hospital

farhanshaikh74@gmail.com9866007602

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026