Health Condition 1: P00-P96- Certain conditions originating in the perinatal period Health Condition 2: A00-B99- Certain infectious and parasitic diseases Health Condition 3: Q00-Q99- Congenital malformations, deformations and chromosomal abnormalities Health Condition 4: D50-D89- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism Health Condition 5: K00-K95- Diseases of the digestive system Health Condition 6: N00-N99- Diseases of the genito
Conditions
Interventions
Intervention1: ketamine and paracetamol: Infant will receive opioid free anesthesia that is Ketamine bolus of 0.5 mg per kg at induction followed by infusion of 0.2 mg per kg per hr and Paracetamol 10
Sponsors
Department of Anesthesiology and critical care aiims jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: Neonates and infants with ASA 1 and 2 undergoing laparoscopic or endoscopic surgeries
Exclusion criteria
Exclusion criteria: 1. Refusal of informed parental consent 2. Patient with prior hypersensitivity to the drug 3. Patient with clinical hypertension 4. Requirement of postoperative mechanical ventilation 5. Patient undergoing cardiac or thoracic surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare postoperative pain in post anesthesia care unit between opioid based and opioid free anesthesiaTimepoint: arrival to post anesthetic care unit and at 30 minute, 1 hour, 2 hour, 6 hour, and 12 hour | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare postoperative pain scores at 30 minute 1 hour 2 hour 6 hour and 12 hour To compare the time of 1st postoperative rescue analgesic requirement To compare time of extubation from stopping study drug infusion To compare intraoperative haemodynamic stability To compare the duration of PACU stay To compare the incidence of any side effect Timepoint: pain scores at 30 minute 1 hour 2 hour 6 hour and 12 hour | — |
Countries
India
Contacts
Public ContactL Pfokreni
Aiims Jodphur
Outcome results
None listed