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A clinical study to find the effect of ketamine to reduce labour pain

EFFECT OF LOW DOSE KETAMINE INFUSION WHEN ADDED TO CONTINUOUS EPIDURAL LABOUR ANALGESIA IN SECOND STAGE OF LABOUR-A RANDOMISED CONTROLLED TRIAL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/05/042788
Enrollment
60
Registered
2022-05-24
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: ketamine: Inj ketamine 0.2mg/kg/hr iv infusion till baby delivery Control Intervention1: Normal saline: Normal saline infusion 5ml/hr iv till baby delivery

Sponsors

SRM Medical college hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All consenting primigravidae having normal vaginal delivery, assessed under ASA 1 and 2, weight between 50 to 100kgs, height more than 150cm and less than 180cm, singleton pregnancy with cephalic presentation with 3cm cervical dilatation after obstetricians approval.

Exclusion criteria

Exclusion criteria: patients who refuse to participate in the study, patients with epilepsy,hyperthyroidism,liver, cardiac,renal disease, coagulation abnormalities and contraindications to epidural anaesthesia.

Design outcomes

Primary

MeasureTime frame
To study the VAS score during second stage of labourTimepoint: Pain will be assessed by visual analogue scale every 30 minutes during labour and continued for 1 hour after baby delivery

Secondary

MeasureTime frame
1. changes in haemodynamic parameters 2. APGAR score 3. Frequency of adverse effectsTimepoint: 1. The heart rate, mean arterial pressure and oxygen saturation will be monitored continuously and recorded every 30 min during the second stage of labour. 2. The APGAR score at 1 minute and 5 minutes will be recorded. 3.Adverse effects will be noted and graded according to severity.

Countries

India

Contacts

Public ContactRajagopalan Venkatraman

SRM medical college hospital and research centre

drvenkat94@gmail.com09894581455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026