Comparing two techniques using blood derived product for treatment of thin gum tissues in healthy individuals.

Comparative evaluation of the injectable platelet rich fibrin (i-PRF) with and without micro-needling for gingival augmentation in thin gingival phenotype - A randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/05/042683

Enrollment

Registered

2022-05-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R69- Illness, unspecified

Interventions

Intervention1: gingival augmentation using injectable platelet rich fibrin along with microneedling technique. : the entire procedure will be performed under local anesthesia and aseptic conditions. o

Eligibility

Inclusion criteria

Inclusion criteria: Age18- 45years. Gingival thickness of mandibular anterior and premolars with thin gingival phenotype (= 0.8mm.) No blood borne conditions. Full mouth plaque index and Bleeding on probing score =15% (total score should be less than =15% of the maximum score). Systemically healthy patients.

Exclusion criteria

Exclusion criteria: Active orthodontic treatment. Use of tobacco in any form. Previous periodontal surgery. Systemic diseases. Use of blood thinners. Use of any drug that might lead to gingival enlargement. Bruxism. Malocclusion, crowding, fillings, missing and supernumerary teeth.

Design outcomes

Primary

Measure	Time frame
To compare the changes in gingival thickness, keratinized tissue width, clinical attachment level and probing depth . Timepoint: Baseline, 1month, 3months and 6months.	—

Secondary

Measure	Time frame
To compare the changes in plaque index, gingival index and modified sulcular bleeding index.Timepoint: Baseline, 6months	—

Countries

India

Contacts

Public ContactSREENIVAS NAGARAKANTI

Narayana dental college and hospital

sreenivasnagarakanti@gmail.com9985664566

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026