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Comparison of effect of 2 methods of giving oxygen: at high flow rate vs traditional oxygen delivery to obese patients after fastrack (surgery with fast recovery) heart surgery with on atelectasis (air sacs of lung do not fill with air) in which the patients will be randomly divided into groups

Comparison of high flow nasal oxygen and conventional oxygen therapy on postoperative atelectasis in obese patients after cardiac surgery with fast track extubation: a randomised control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/05/042678
Enrollment
72
Registered
2022-05-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I00-I99- Diseases of the circulatory system Health Condition 2: E669- Obesity, unspecified

Interventions

Intervention1: Group H- HFNO group : Group H-Patients will be kept on HFNO after extubation in the postoperative period. HFNO settings: oxygen flow 30-50 L/min, FiO2 will be titrated to maintain SpO

Sponsors

King Georges Medical University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA physical status III and IV with BMI >= 30 kg/m2 scheduled to undergo elective cardiac surgery with fast track extubation will be included in this trial.

Exclusion criteria

Exclusion criteria: 1)Heart failure 2)Vasopressor support 3)Severe Pulmonary Hypertension 4)Preoperative atelectasis 5)Preoperative pulmonary disease including - tuberculosis, pleural effusion, restrictive lung disease, COPD , Asthma 6)Contraindication to HFNO including blocked nasal passage / choanal atresia , Trauma / surgery to nasopharynx 7)Negative consent/refusal

Design outcomes

Primary

MeasureTime frame
Incidence of atelectasis after surgery Timepoint: On the day of surgery (in the immediate postoperative period), One day after surgery and Two days after surgery—

Secondary

MeasureTime frame
1. Severity of atelectasis 2. Vitals: Heart rate, Blood Pressure, Respiratory Rate, Oxygen saturation and temperature. 3. Dyspnea Score using modified Borg score 4. Pain score using Visual analogue scale 5. PaO2/PiO2 ratio, PCO2, and PaO2 using arterial blood gas 6. Shunt fraction 7. Duration of oxygen requirement 8. Duration of ICU stay 9. Re-intubation rateTimepoint: Outcome 1-after extubation, day 1 & 3 of surgery Outcomes 2,3 & 4 -every 2 hour for 12 hours then day 1,2 & 3 Outcome 5 & 6-after extubation, day 1, day2,day3 Outcome 7,8 & 9- in the postoperative period—

Countries

India

Contacts

Public ContactRajesh Raman

King Georges Medical University

ramanrajesh83@gmail.com7905912607

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026