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Comparative Evaluation of Resistin levels in Gingival Crevicular Fluid and Saliva of Patients with Hypertension and Periodontitis

Comparative Evaluation of Resistin levels in Gingival Crevicular Fluid and Saliva of Patients with Hypertension and Chronic Periodontitis â?? An In vivo biochemical Study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/05/042673
Enrollment
80
Registered
2022-05-19
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: I159- Secondary hypertension, unspecified

Interventions

None listed

Sponsors

DR VARSHA URLAM
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria: a) Patients who are 18 years and above who are willing to participate. b) Presence of at least 20 natural teeth excluding third molars. c) Chronic periodontitis as stated by American Academy of Periodontology (AAP) classification 2018: presence of > 2 teeth in each quadrant with a PPD of > 5mm, CAL of > 4mm and radiographic evidence of interproximal bone loss. Along with BOP at >50% of sites of full mouth. d) Patients who are hypertensive as per Blood pressure classification as given by American Heart Association 2017 guidelines for prevention, detection, evaluation and management of High Blood Pressure in adults.

Exclusion criteria

Exclusion criteria: a) Patients with any other known systemic disorder. b) Patients who have received any form of periodontal therapy, surgical or non-surgical within past 6 months. c) Patients who have received any antibiotic or anti-inflammatory drug regimen within past 6 months. d) Patients who smoke or chew any form of tobacco. e) Patients who are pregnant or lactating. f) Patients who are undergoing any orthodontic treatment. g) Physically and mentally challenged patients. h) Patients prone to or with a history of allergic reactions to any component of the investigating materials.

Design outcomes

Primary

MeasureTime frame
1. To comparatively evaluate Resistin levels in GCF and saliva of patients with Hypertension and Chronic Periodontitis. 2. To assess and evaluate the role of Resistin as a diagnostic biomarker in patients of Hypertension and Chronic Periodontitis. Timepoint: 1 DAY—

Secondary

MeasureTime frame
To assess and evaluate the role of Resistin as a diagnostic biomarker in patients of Hypertension and Chronic Periodontitis.Timepoint: 1 DAY—

Countries

India

Contacts

Public ContactDR ASHVINI PADHYE

MGM DENTAL COLLEGE AND HOSPITAL

drashvini16@gmail.com9820138480

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026