FindTrial
Sign In

The study to compare the effect of 3 intravenous drugs namely Dexmedetomidine,Midazolam and fentanyl in the effect of spinal Anesthesia duration and also the efficacy of sedation caused by these 3 drugs.

Comparison of Prolongation of Spinal Anaesthesia produced by intravenous Dexmedetomidine, Midazolam and Fentanyl: A Randomised Double blinded trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/05/042661
Enrollment
87
Registered
2022-05-19
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Group A- 0.5 mcg/kg loading dose followed by 0.5mcg/kg/hr maintenance Dexmedetomidine for a duration of more than hour and less than 4 hrs. Control Intervention1: Mi

Sponsors

Kripa S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA class 1 & 2 Infraumblical surgeries >1 hr & <4 hrs.

Exclusion criteria

Exclusion criteria: Surgeries 4 hrs. Patient on sedatives,opioids or antidepressants. Pregnant Women. Patient with baseline heart rate <50 beats /min &/SBP <90mmHg.

Design outcomes

Primary

MeasureTime frame
Two dermatomal regression time, from the maximum level of sensory blockadeTimepoint: Immediately after spinal blockade and every 30min thereafter.—

Secondary

MeasureTime frame
Prolongation of Sedation and hemodynamic instability associated with the study drugs Timepoint: Immediately after spinal blockade and at 5 min throughout the procedure and thereafter half an hour till 2hrs post procedure.—

Countries

India

Contacts

Public ContactKripa S

Sri Ramachandra Institute Of Higher Education and Research.

rampond@gmail.com9380537411

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026