Health Condition 1: E112- Type 2 diabetes mellitus with kidney complications
Conditions
Interventions
Intervention1: Not applicable: Not applicable
Control Intervention1: Not applicable: Not applicable
Sponsors
Thakurpukur Medical Society
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosed case of Diabetic Kidney Disease Type 2 Diabetes Mellitus with a. Urinary Spot ACR > 30 mg/g and / or b. eGFR, calculated by CKD-EPI c. Receiving RAAS-I for at least 4 weeks d. Recently initiated on SGLT2-I
Exclusion criteria
Exclusion criteria: 1. eGFR, calculated by CKD-EPI 2. Non-consenting patients 3. Doubt about the nature of kidney disease. Suspicion of nondiabetic renal disease such as renal artery stenosis, glomerular disease or other systemic disorders with renal involvement 4. Ongoing active infection, sepsis or symptomatic UTI, active malignancy 5. History of symptomatic UTI in the past 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite of : 50% decline in eGFR from baseline OR eGFR falling below 15 ml/min/1.73m2 OR initiation of hemodialysis Timepoint: 58 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 50% reduction in albuminuria OR albuminuria decreasing from A3 to A2/A1 or A2 to A1Timepoint: 58 weeks;eGFR at the end of the study periodTimepoint: 58 weeks;Major Cardiovascular End Points: Occurrence of Myocardial infarction, stroke, hospitalisation due to heart failure or deathTimepoint: any time up to 58 weeks | — |
Countries
India
Contacts
Public ContactDr Susovan Halder
Thakurpukur Medical Society
Outcome results
None listed