Health Condition 1: I10- Essential (primary) hypertension
Conditions
Interventions
Intervention1: Topical lidocaine: Injection Lignocaine 1.5 mg/kg applied topically using atomiser over a period of 30 seconds
Control Intervention1: Intravenous lidocaine: Injection lidocaine 1.5 mg/k
Sponsors
Nil
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients between 18 â?? 80 years belonging to American Society of Anesthesiologists grade II with controlled hypertension ( Preoperative blood pressure less than 140/90 mm of Hg, controlled using single or combination of antihypertensive drugs)undergoing oro-tracheal intubation. posted for elective non cardiac surgery lasting more than one hour.
Exclusion criteria
Exclusion criteria: 1. Patients with anticipated difficult airway 2. Patients who are allergic to lignocaine 3. Patients with history of ischemic heart disease and any vascular aneurysm 4. Pregnant women 5. Patients with active Gastroesophageal reflux disease GERD 6. Patients with oropharyngeal pathology
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the difference between the preinduction and one minute post intubation systolic arterial pressure, between the atomized topical lidocaine group and intravenous lidocaine group following laryngoscopy and tracheal intubation. Timepoint: pre intubation and one minute post intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Mean arterial pressure 2.Diastolic pressure 3.Heart rate 4.Rate Pressure Product 5.ECG changes 6.Arrhythmias Timepoint: One minute intervals upto 10 minutes post intubation | — |
Countries
India
Contacts
Public ContactDr Sakthirajan P
JIPMER
Outcome results
None listed