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Comparison of postoperative pain for 0.5% hyperbaric bupivacaine given as spinal block with intravenous or spinal dexmedetomidine in abdominal hysterectomy.

Comparison of intravenous and intrathecal dexmedetomidine as adjuvants to 0.5% hyperbaric bupivacaine for post operative analgesia in abdominal hysterectomy.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/05/042588
Enrollment
100
Registered
2022-05-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intrathecal block: Intrathecal block prior surgery using 0.5% hyperbaric bupivacaine 3ml with intrathecal dexmedetomidine 5mcg or intravenous dexmedetomidine 1mcg/kg and Duration of ana

Sponsors

JLN medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.body weight 40 to 80 kg. 2.Patient belonging to ASA class I and II. 3.Patient undergoing abdominal surgery.

Exclusion criteria

Exclusion criteria: 1.Patient refusal or uncooperative patient. 2.Any known hypersensitivity or contraindication to bupivacaine, dexmedetomidine. 3.Local pathology at the site of injection or disability limiting the performance of spinal block. History of convulsion, bleeding disorder, severe neurological deficit, thyroid disorder. Patient with history of respiratory,cardiac,hepatic or renal disease. Patient having a history of significant neurological,psychiatric or neuromuscular disorders.

Design outcomes

Primary

MeasureTime frame
Duration of analgesia.Timepoint: 1 year

Secondary

MeasureTime frame
Onset and recovery(time to 2 segment regression) of sensory block. Onset and recovery of motor block, Peri operative sedation score. Haemodyanamic changes. Adverse effect if any.Timepoint: 1 year

Countries

India

Contacts

Public ContactDr Veena Patodi

J.L.N. medical college and hospital

veenapatodi@gmail.com9414008276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026