Health Condition 1: M844- Pathological fracture, not elsewhere classified Health Condition 2: M844- Pathological fracture, not elsewhere classified
Conditions
Interventions
Intervention1: Ondansetron: 4mg(2 ml) iv route 5 minute brfore spinal anaesthesia
Control Intervention1: Glycopyrrolate: 0.2 mg( diluted to 2 ml normal saline) IV route 5 minute before spinal anaesthe
Sponsors
Caicutta National Medical College And Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients of age 18-45 years, either sex, ASA physical status I & II undergoing elective lower limb orthopaedic surgeries under spinal anaesthesia will be included in this study.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (i) Patients having contraindications for spinal anaesthesia like lack of consent, raised intra cranial tension, infection at local site, severe aortic stenosis, coagulopathy, cardiovascular instability. (ii) Patients with known allergy to study drugs (iii) Patients with BMI > 30 kg/m² (iv) Patients having height (v) Patients ASA physical status III or more (vi) Patients having major cardiovascular, respiratory, renal, hepatic, metabolic, neurological or endocrine diseases. (vii) Patients with glaucoma (viii) Patients receiving any antihypertensive, vasodilator, antiarrhythmic or antiemetic agents (ix) Patients requiring general anaesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of hypotension intraoperatively after giving spinal anaesthesiaTimepoint: 19 months | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of bradycardia, total phenylephrine requirement and total fluid requirement in the intraoperative period.Timepoint: 19 months | — |
Countries
India
Contacts
Public ContactDr Palas halder
Calcutta National medical college
Outcome results
None listed