Health Condition 1: O754- Other complications of obstetric surgery and procedures
Conditions
Interventions
Intervention1: In Non-laboring Obese patients: Titrated dose of intravenous oxytocin infusion: The dose of the infusion will be 13IU/h(0.22IU/min) for the first patient.Dosing interval (increase) for
Sponsors
UCMS and GTBH
Eligibility
Inclusion criteria
Inclusion criteria: All non-laboring parturient >18 years age will be enrolled. The two arms will include obese (body mass index >=30 kg/m2) or non-obese pregnant patients (body mass index
Exclusion criteria
Exclusion criteria: Exclusion criteria shall be patient refusal, presence of labor (defined as cervical dilatation of 3 cm or more), use of oxytocin in the preoperative period, history of PPH or more than one previous uterine surgery as well as bleeding disorders, presence of abnormal placentation and uterine fibroid, contraindications to spinal block, such as hemodynamic instability, infection at the injection site, and coagulopathy (thrombocytopenia with platelet count 1.5).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The calculated ED90 of prophylactic oxytocin infusion in both cohortsTimepoint: The status of uterine tone assessed by the operating obstetrician ( satisfactory or unsatisfactory) at 4-minute post oxytocin intiation. | — |
Secondary
| Measure | Time frame |
|---|---|
| The requirement of additional uterotonic drugs.Timepoint: From cord clamping to end of surgery. | — |
Countries
India
Contacts
Public ContactDr Asha Tyagi
University College of Medical Sciences and GTB Hospital
Outcome results
None listed