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A study to compare duration of pain relief for chloroprocaine with or without dexmedetomidine in elective caesarean section in spinal anaesthesia

A COMPARATIVE STUDY TO EVALUATE THE EFFICACY OF DEXMEDETOMIDINE(5µg) USED AS AN ADJUVANT TO ISOBARIC 1% 2-CHLOROPROCAINE IN PARTURIENTS UNDERGOING ELECTIVE LOWER SEGMENT CAESAREAN SECTION UNDER SUBARACHNOID BLOCK

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/05/042426
Enrollment
100
Registered
2022-05-10
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication Health Condition 2: 1- Obstetrics

Interventions

Intervention1: Intrathecal block: Duration of sensory block is assessed after intrathecal block given before surgery with 3ml 1% 2-chloroprocaine with or without dexmedetomidine and duration of study

Sponsors

JLN Medical college hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status II Parturients who will undergo elective uncomplicated or low risk lower segment caesarean section

Exclusion criteria

Exclusion criteria: Age 35years. Parturient refusal. ASA physical status III and above. Parturient with body mass index(BMI) >35kg/m2. Parturient with hypersensitivity/allergic to local anaesthetic agents or study drug(dexmedetomidine). Parturient with any known cardiac,renal or hepatic disease. Parturient with pre-existing peripheral neuropathy or neurological deficit. Parturient on anticoagulants. Infection at the site of lumbar puncture. Contraindications of subarachnoid block.

Design outcomes

Primary

MeasureTime frame
Duration of sensory block/analgesia.Timepoint: Intraoperatively and postoperatively—

Secondary

MeasureTime frame
Onset of sensory block. Two segment regression of sensory block. Onset and duration of motor block. Quality of analgesia. Visual analogue scale(VAS) score. Duration of analgesia. Neonatal outcome(APGAR score). Haemodynamics(HR,SBP,DBP and MAP) Side effects/complications like nausea,vomiting,bradycardia,hypotension,respiratory depression,sedation, if any.Timepoint: Intraoperatively and postoperatively—

Countries

India

Contacts

Public ContactDr Beena Thada

JLN medical college, ajmer

drbeenaverma@gmail.com9352260425

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026