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Comparison of effects of wound infiltration with Dexamethasone versus Dexmedetomidine with Ropivacaine on post operative pain in Laparoscopic Cholecystectomy

Comparison of effects of port site infiltration with Dexamethasone versus Dexmedetomidine as adjuvant to Ropivacaine on post operative analgesia in Laparoscopic Cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/05/042384
Enrollment
60
Registered
2022-05-05
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexamethasone: Before closure of surgical wound, all 4 port sites will be infiltrated with Ropivacaine (0.5%) 20mL plus dexamethasone 8mg diluted in NS to make 4mL (total volume-24mL)

Sponsors

sharda hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective laparoscopic cholecystectomy through four ports under general anaesthesia. 2. ASA class I and II 3. Age 18-60 years 4. Both genders

Exclusion criteria

Exclusion criteria: 1. Patients receiving steroids, analgesics, antiemetic and sedatives. 2. Patients with past history of chronic pain. 3. Patients having history of endocrine, cardiovascular, renal or CNS disease. 4. Patients allergic to study drugs. 5. BMI > 30 kg m-2

Design outcomes

Primary

MeasureTime frame
To compare the post operative pain score following port site infiltration with dexamethasone versus dexmedetomidine as adjuvant to ropivacaine (0.5%) in the patients of laparoscopic cholecystectomy. Timepoint: upto 24 hours

Secondary

MeasureTime frame
1.To compare the duration of post operative analgesia in three groups 2. To compare the hemodynamic parameters (HR, SBP, DBP, MAP) post operatively 3. To compare the incidence of PONV in three groups 4. To compare the sedation score in three groups Timepoint: 24 hours

Countries

India

Contacts

Public ContactDr Nupur Aggarwal

school of medical sciences and research

mahendra.kumar@sharda.ac.in8287188449

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026