A clinical trial to study the effect of antioxidants in the management of temporomandibular disorders

Evaluation of therapeutic role of antioxidants in the management of temporomandibular disorders

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/04/042337

Enrollment

Registered

2022-04-29

Start date

Unknown

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Systemic antioxidants, topical anti-inflammatory and jaw exercises: tablet antoxid 10 mg OD x 30 days Topical 5 % Flurbiprofen Gel and Jaw exercises Control Intervention1: Topical ant

Eligibility

Inclusion criteria

Inclusion criteria: 1. Muscle related pain, disc-condylar changes (DC/TMD) 2. 30mm VAS 3. All age groups

Exclusion criteria

Exclusion criteria: Pain due to odontogenic pathologies Neuropathic pain Atypical facial pain Patients with co-morbidities

Design outcomes

Primary

Measure	Time frame
Level of Malondialdehyde total antioxidant capacityTimepoint: one month	—

Secondary

Measure	Time frame
VAS score Mouth openingTimepoint: one month	—

Countries

India

Contacts

Public ContactDr Arvind M

Saveetha dental college

arvindmuthukrishnan@yahoo.com9444303303

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026